Having shown his worth during the Battle of Hellawes in which he battled an army of Fullmetal Father Drones, Mustang became a member of the Jump Force under the leadership of Shepard Sorey. However Mustang soon came into conflict with his teammates when he and Edward Elric sided with Kakashi Hatake on the Hellawes Accords. This eventually led to a full-blown conflict between the heroes, with Mustang taking his friend Edward's side. During a battle with Sorey, Mustang was badly injured and nearly paralyzed from a friendly-fire attack, forcing him to retire from hero work.
Mustang returned to the Jump Force after a hiatus, becoming the team's liaison with the United Nations. Mustang disobeyed the Hellawes Accords when he joined Sorey traveling to Shura, earning a court martial in the process. Mustang participated in the Battle of Shura and alongside the other Jump Force members and Shuran armies as well as the Soul Guardians killed all of Omega Shenron's soldiers, only to be soon faced and effortlessly beaten by Omega Shenron when he came personally to Shura alongside the other heroes, with Omega Shenron successfully wiping out half of the universe after acquiring all the Dragon Balls. Mustang was one of the survivors.
Flame Alchemy: Even among the elite State Alchemists, Colonel Mustang is a particularly skilled alchemist adequately versed in standard physical transmutation, experimental theory and biological alchemy. However, the brilliant skill that has earned him his state license, national notoriety and the status of "hero" is his remarkably powerful fire-based combat style. Mustang's unique style of combat alchemy is made possible by his custom made gloves. Made of "pyrotex/ignition cloth," these gloves create a spark when Roy rubs his fingers together, and embroidered with unique flame alchemy Transmutation Circles, they allow him to manipulate the concentration of oxygen in the air. When attacking, Mustang raises the density of the oxygen surrounding his target to a level at which it becomes volatile and creates narrow pathways of oxygen between himself and his target through which he can direct the ensuing flash fire that blossoms from the spark of his gloves. As a result, he can incinerate any number of enemies in the field while deftly avoiding any adjacent allies. The 'snap' sound heard at the start of these transmutations is caused by the instantaneous speed at which the highly concentrated gases and sparks react together and pop (and not Mustang's fingers actually 'snapping', to common belief.)
It has also been revealed that Roy is able to delegate each hand to a different flame effect, possibly due to a difference in hand dexterity. The right hand appears to allow for large explosive attacks, while the left allows for smaller, but strong and very accurate pinpoint flame attacks.
While Mustang's Flame Alchemy cannot be used on rainy days because the humidity makes it impossible for his gloves to produce sparks, it becomes clear that water itself does not make the Colonel entirely as "useless" as his subordinates assume. Using the transmutation circles on his gloves, Roy is able to separate hydrogen atoms from the oxygen atoms in water molecules, isolating them into a highly combustible fuel and powerfully volatile oxidizer, respectively. Though this method can only be used when a large quantity of water is present in a relatively closed-off space (and not in the rain where the air is open and separating hydrogen and oxygen for the purpose of combustion would pose far too much danger to anyone in the vicinity), with an outside source of ignition such as a cigarette lighter or a match, Roy can produce extremely powerful, localized explosions.